CRHR1 Protein (AA 23-121) (His tag)
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- 抗原 See all CRHR1 蛋白
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-121
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宿主
- 人
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资源
- 酵母菌
- 标记
- This CRHR1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MSLQDQHCES LSPASNVSGL QCNASVDLIG TCWPRSPARQ LVVRPCPAFF YGVRYNTTNN GYRECLANGS WAARVNYSEC QEILNEEKKS KVHYHVAVI
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product CRHR1 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
- 别名
- CRFR1 (CRHR1 产品)
- 别名
- CRF-R Protein, CRF-R-1 Protein, CRF-R1 Protein, CRF1 Protein, CRFR-1 Protein, CRFR1 Protein, CRH-R-1 Protein, CRH-R1 Protein, CRH-R1h Protein, CRHR Protein, CRHR1L Protein, CRHR1f Protein, Crhr Protein, crhr1 Protein, crhr1-A Protein, CRHR1 Protein, CRHR1-IT1-CRHR1 Protein, MGC57346-CRHR1 Protein, corticotropin releasing hormone receptor 1 Protein, corticotropin releasing hormone receptor 1, gene 2 S homeolog Protein, corticotropin-releasing factor receptor 1 Protein, LINC02210-CRHR1 readthrough Protein, CRHR1 Protein, Crhr1 Protein, crhr1.2.S Protein, LOC610380 Protein, LOC100065598 Protein, LINC02210-CRHR1 Protein, crhr1 Protein
- 背景
- G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal bryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
- 分子量
- 13.1 kDa
- UniProt
- P34998
- 途径
- Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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