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MIB1 Protein (AA 5-332, partial) (His tag)

MIB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5712848
发货至: 中国
  • 抗原 See all MIB1 蛋白
    MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
    蛋白类型
    Recombinant
    产品特性
    AA 5-332, partial
    宿主
    • 5
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This MIB1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    RNNRVMVEGV GARVVRGPDW KWGKQDGGEG HVGTVRSFES PEEVVVVWDN GTAANYRCSG AYDLRILDSA PTGIKHDGTM CDTCRQQPII GIRWKCAECT NYDLCTVCYH GDKHHLRHRF YRITTPGSER VLLESRRKSK KITARGIFAG ARVVRGVDWQ WEDQDGGNGR RGKVTEIQDW SASSPHSAAY VLWDNGAKNL YRVGFEGMSD LKCVQDAKGG SFYRDHCPVL GEQNGNRNPG GLQIGDLVNI DLDLEIVQSL QHGHGGWTDG MFETLTTTGT VCGIDEDHDI VVQYPSGNRW TFNPAVLTKA NIVRSGDAAQ GAEGGTSQ
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product MIB1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
    别名
    MIB1 (MIB1 产品)
    别名
    DIP-1 Protein, DIP1 Protein, LVNC7 Protein, MIB Protein, ZZANK2 Protein, ZZZ6 Protein, E430019M12Rik Protein, Mib Protein, mKIAA1323 Protein, dip-1 Protein, mib Protein, mindbomb Protein, cg5841 Protein, chunp6889 Protein, fe47f05 Protein, im:7148100 Protein, mib1 Protein, wu:fe47f05 Protein, CG5841 Protein, D-mib Protein, D-mib1 Protein, Dmel\CG5841 Protein, Dmib Protein, MIB1 Protein, Mib1 Protein, dmib1 Protein, l(3)72CDa Protein, l(3)72Db Protein, mib1/2 Protein, mind-bomb Protein, mindbomb E3 ubiquitin protein ligase 1 Protein, mindbomb E3 ubiquitin protein ligase 1 L homeolog Protein, mind bomb 1 Protein, MIB1 Protein, Mib1 Protein, mib1.L Protein, mib1 Protein
    背景
    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis . Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.1 Publication
    分子量
    40.2 kDa
    UniProt
    Q86YT6
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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