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PICK1 Protein (AA 1-200, partial) (GST tag)

PICK1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5712409
发货至: 中国
  • 抗原 See all PICK1 蛋白
    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
    蛋白类型
    Recombinant
    产品特性
    partial, AA 1-200
    宿主
    • 6
    • 3
    • 1
    • 1
    • 1
    资源
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This PICK1 protein is labelled with GST tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MFADLDYDIE EDKLGIPTVP GKVTLQKDAQ NLIGISIGGG AQYCPCLYIV QVFDNTPAAL DGTVAAGDEI TGVNGRSIKG KTKVEVAKMI QEVKGEVTIH YNKLQADPKQ GMSLDIVLKK VKHRLVENMS SGTADALGLS RAILCNDGLV KRLEELERTA ELYKGMTEHT KNLLRAFYEL SQTHRAFGDV FSVIGVREPQ
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product PICK1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
    别名
    PICK1 (PICK1 产品)
    别名
    PICK Protein, PRKCABP Protein, Prkcabp Protein, prkcabp Protein, MGC131295 Protein, PICK1 Protein, DKFZp470L2127 Protein, protein interacting with PRKCA 1 Protein, protein interacting with C kinase 1 Protein, protein interacting with PRKCA 1 L homeolog Protein, PICK1 Protein, Pick1 Protein, pick1 Protein, pick1.L Protein
    背景
    Probable adapter protein that bind to and organize the subcellular localization of a variety of mbrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
    分子量
    49.3 kDa
    UniProt
    Q9NRD5
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