TRIM11 Protein (AA 267-468, partial) (His-SUMO Tag)
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- 抗原 See all TRIM11 蛋白
- TRIM11 (Tripartite Motif Containing 11 (TRIM11))
- 蛋白类型
- Recombinant
- 产品特性
- AA 267-468, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TRIM11 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MELRTVCRVP GLVETLRRFR GDVTLDPDTA NPELILSEDR RSVQRGDLRQ ALPDSPERFD PGPCVLGQER FTSGRHYWEV EVGDRTSWAL GVCRENVNRK EKGELSAGNG FWILVFLGSY YNSSERALAP LRDPPRRVGI FLDYEAGHLS FYSATDGSLL FIFPEIPFSG TLRPLFSPLS SSPTPMTICR PKGGSGDTLA PQ
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TRIM11 蛋白
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Tripartite Motif Containing 11 (TRIM11) (AA 132-230) protein (GST tag)
TRIM11 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Tripartite Motif Containing 11 (TRIM11) (AA 1-468) protein (Strep Tag)Crystallography grade TRIM11 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Tripartite Motif Containing 11 (TRIM11) (AA 1-467) protein (Strep Tag)Crystallography grade TRIM11 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Tripartite Motif Containing 11 (TRIM11) protein (Myc-DYKDDDDK Tag)TRIM11 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TRIM11 (Tripartite Motif Containing 11 (TRIM11))
- 别名
- TRI11 (TRIM11 产品)
- 别名
- BIA1 Protein, RNF92 Protein, TRIM11 Protein, tripartite motif containing 11 Protein, tripartite motif-containing 11 Protein, TRIM11 Protein, Trim11 Protein
- 背景
- E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle.
- 分子量
- 38.5 kDa
- UniProt
- Q96F44
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