SAMHD1 Protein (AA 395-626) (His tag)
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- 抗原 See all SAMHD1 蛋白
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 395-626
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This SAMHD1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- DIMITDAFLK ADPYVEITGT AGKKFRISTA IDDMEAFTKL TDNIFLEVLH STDPQLSEAQ SILRNIECRN LYKYLGETQP KREKIRKEEY ERLPQEVAKA KPEKAPDVEL KAEDFIVDVI NVDYGMEDKN PIDRVHFYCK SNSKQAVRIN KEQVSQLLPE KFAEQLIRVY CKKKDGKSLD AAGKHFVQWC ALRDFTKPQD GDIIAPLITP LKWNNKTSSC LQEVSKVKTC LK
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product SAMHD1 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
- 别名
- SAMH1 (SAMHD1 产品)
- 背景
- Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling .
- 分子量
- 30.7 kDa
- UniProt
- Q60710
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