PTPRB Protein (AA 1643-1997) (His-SUMO Tag)
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- 抗原 See all PTPRB 蛋白
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1643-1997
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PTPRB protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- RQKVSHGRER PSARLSIRRD RPLSVHLNLG QKGNRKTSCP IKINQFEGHF MKLQADSNYL LSKEYEELKD VGRNQSCDIA LLPENRGKNR YNNILPYDAT RVKLSNVDDD PCSDYINASY IPGNNFRREY IVTQGPLPGT KDDFWKMVWE QNVHNIVMVT QCVEKGRVKC DHYWPADQDS LYYGDLILQM LSESVLPEWT IREFKICGEE QLDAHRLIRH FHYTVWPDHG VPETTQSLIQ FVRTVRDYIN RSPGAGPTVV HCSAGVGRTG TFIALDRILQ QLDSKDSVDI YGAVHDLRLH RVHMVQTECQ YVYLHQCVRD VLRARKLRSE QENPLFPIYE NVNPEYHRDP VYSRH
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product PTPRB 蛋白
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Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1643-1997) protein (His tag)
Crystallography grade PTPRB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1644-1997) protein (His tag)Crystallography grade PTPRB 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 23-1621) protein (His tag)Crystallography grade PTPRB 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 23-1622) protein (His tag)Crystallography grade PTPRB 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (AA 1643-1997) protein (His tag)PTPRB 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PTPRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
- 别名
- PTPRB (PTPRB 产品)
- 别名
- PTPRB Protein, HPTP-BETA Protein, HPTPB Protein, PTPB Protein, R-PTP-BETA Protein, VEPTP Protein, 3230402H02Rik Protein, C130094E24 Protein, Ptpz Protein, Rptpb Protein, VE-PTP Protein, Veptp Protein, protein tyrosine phosphatase, receptor type B Protein, receptor-type tyrosine-protein phosphatase beta Protein, protein tyrosine phosphatase, receptor type, B Protein, PTPRB Protein, LOC100380677 Protein, Ptprb Protein
- 背景
- Plays an important role in blood vessel rodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and rodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel rodeling during bryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin .
- 分子量
- 57.36 kDa
- UniProt
- P23467
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