IL12B Protein (AA 23-327) (His tag)
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- 抗原 See all IL12B 蛋白
- IL12B (Interleukin 12 beta (IL12B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-327
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宿主
- 绵羊
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IL12B protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- IWELEKNVYV VELDWYPNAP GETVVLTCDT PEEDGITWTS DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSRSLL LLHKKEDGIW STDILKDQKE PKAKSFLKCE AKDYSGHFTC SWLTAISTNL KFSVKSSRGS SDPRGVTCGA ASLSAEKVSM DHREYNKYTV ECQEGSACPA AEESLPIEVV MEAVHKLKYE NYTSSFFIRD IIKPDPPKNL QLRPLKNSRQ VEVSWEYPDT WSTPHSYFSL TFCVQVQGKN KREKKLFTDQ TSAKVTCHKD ANIRVQARDR YYSSFWSEWA SVSCS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product IL12B 蛋白
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Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)
IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: 人 宿主: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. WB, Imm
Interleukin 12 beta (IL12B) (AA 23-328) proteinIL12B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant SDS
Interleukin 12 beta (IL12B) protein (His tag)IL12B 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interleukin 12 beta (IL12B) (AA 229-328) protein (GST tag)IL12B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: 人 宿主: Insect Cells Recombinant SDS
Interleukin 12 beta (IL12B) (AA 23-335) protein (His tag)Crystallography grade IL12B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 12 beta (IL12B) (AA 23-328) protein (Fc Tag)IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Interleukin 12 beta (IL12B) (AA 23-328) (Active) protein (His tag)IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- IL12B (Interleukin 12 beta (IL12B))
- 别名
- IL12B (IL12B 产品)
- 别名
- CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, IL-12 p40 Protein, il12b Protein, il12p40.b Protein, zgc:152789 Protein, IL-12.p40 Protein, IL12p40 Protein, IL12B Protein, CLMF p40 Protein, interleukin 12B Protein, interleukin 12b Protein, interleukin 12Ba Protein, IL12B Protein, Il12b Protein, il12ba Protein
- 背景
- Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates mory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis .
- 分子量
- 38.6 kDa
- UniProt
- P68220
- 途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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