Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
H2A.1b Protein, H2A/p Protein, H2AFP Protein, H2AG Protein, pH2A/f Protein, histone cluster 1 H2A family member g Protein, histone H2A type 1 Protein, similar to Histone H2A type 1 Protein, HIST1H2AG Protein, LOC786163 Protein, LOC680322 Protein, LOC104968446 Protein
背景
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.