PDCD1LG2 Protein (AA 20-219) (Fc Tag)
(1 reference)-
- 抗原 See all PDCD1LG2 蛋白
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-219
-
宿主
- 小鼠
-
资源
- HEK-293 Cells
- 标记
- This PDCD1LG2 protein is labelled with Fc Tag.
- 应用范围
- Functional Studies (Func)
- 序列
- AA 20-219
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.2 kDa. As a result of glycosylation, the protein migrates as 60-70 kDa under reducing (R) condition, and 120-140 kDa under non-reducing (NR) condition (SDS-PAGE).
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PDCD1LG2 蛋白
-
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (His-Avi Tag)
PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His tag)PDCD1LG2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-220) protein (His-Avi Tag,Biotin)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (Fc Tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-121) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 19-220) protein (His-DYKDDDDK-Strep II Tag)PDCD1LG2 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) protein (His tag)PDCD1LG2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (His tag,AVI tag,Biotin)PDCD1LG2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) protein (Fc Tag)PDCD1LG2 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
-
-
: "Quantitative phosphoproteomic analysis reveals involvement of PD-1 in multiple T cell functions." in: The Journal of biological chemistry, Vol. 295, Issue 52, pp. 18036-18050, (2020) (PubMed).
-
: "Quantitative phosphoproteomic analysis reveals involvement of PD-1 in multiple T cell functions." in: The Journal of biological chemistry, Vol. 295, Issue 52, pp. 18036-18050, (2020) (PubMed).
-
- 抗原
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 别名
- PD-L2 (PDCD1LG2 产品)
- 别名
- PDL2 Protein, B7DC Protein, Btdc Protein, CD273 Protein, PD-L2 Protein, PDCD1L2 Protein, bA574F11.2 Protein, B7-DC Protein, F730015O22Rik Protein, programmed cell death 1 ligand 2 Protein, PDCD1LG2 Protein, Pdcd1lg2 Protein
- 背景
- Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
- 分子量
- 49.2 kDa
- NCBI登录号
- NP_067371
-
