CD51/CD61 Protein (AA 31-992) (His tag)
(1 reference)-
- 抗原 See all CD51/CD61 (ITGAV/ITGB3) 蛋白
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 31-992
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD51/CD61 protein is labelled with His tag.
- 序列
- AA 31-992
- 产品特性
- Human ITGAV & ITGB3 Heterodimer Protein, produced by co-expression of ITGAV and ITGB3, has a calculated MW of 113 kDa (ITGAV) and 81.8 kDa (ITGB3). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB3 contains no tag but a basic tail at the C-terminus. The predicted N-terminus is Phe 31 (ITGAV) & Gly 27 (ITGB3). The reducing (R) protein migrates as 145 kDa (ITGAV) and 100-116 kDa (ITGB3) respectively due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product ITGAV/ITGB3 蛋白
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Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) (AA 31-992) protein (His-Avi Tag)
ITGAV/ITGB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) (AA 31-992) protein (Fc Tag)ITGAV/ITGB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) (AA 31-992) protein (His-Avi Tag,Biotin)ITGAV/ITGB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) (AA 31-988) protein (Fc Tag)ITGAV/ITGB3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) (AA 31-988) protein (His tag)ITGAV/ITGB3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 150 mM NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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: "Radioiodinated bicyclic RGD peptide for imaging integrin αvβ3 in cancers." in: Biochemical and biophysical research communications, Vol. 528, Issue 1, pp. 168-173, (2021) (PubMed).
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: "Radioiodinated bicyclic RGD peptide for imaging integrin αvβ3 in cancers." in: Biochemical and biophysical research communications, Vol. 528, Issue 1, pp. 168-173, (2021) (PubMed).
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- 抗原
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- 别名
- Integrin alpha V beta 3 (ITGAV/ITGB3 产品)
- 别名
- CD51 Protein, MSK8 Protein, VNRA Protein, VTNR Protein, integrin subunit alpha V Protein, ITGAV Protein
- 背景
- Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
- 分子量
- 112.9 kDa (ITGAV) & 81.8 kDa (ITGB3)
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