FZD5 Protein (AA 27-180) (Fc Tag)
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- 抗原 See all FZD5 蛋白
- FZD5 (Frizzled Family Receptor 5 (FZD5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 27-180
- 宿主
- 人, 小鼠
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资源
- HEK-293 Cells
- 标记
- This FZD5 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 特异性
- Binds to human and mouse Wnt3a.
- 交叉反应
- 人, 小鼠
- 产品特性
- The cysteine-rich domain (CRD) of human Frizzled-5 (aa 27-180) is fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FZD5 蛋白
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Frizzled Family Receptor 5 (FZD5) (AA 1-585) protein (GST tag)
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Frizzled Family Receptor 5 (FZD5) (AA 72-161) protein (GST tag)FZD5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 5 (FZD5) protein (Fc Tag)FZD5 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as determined by SDS-PAGE
Frizzled Family Receptor 5 (FZD5) (AA 27-238) protein (His tag)Crystallography grade FZD5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-238) protein (His tag)Crystallography grade FZD5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-585) protein (rho-1D4 tag)Crystallography grade FZD5 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-585) protein (rho-1D4 tag)Crystallography grade FZD5 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
Frizzled Family Receptor 5 (FZD5) (AA 27-167) protein (Fc Tag)FZD5 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Inhibits Wnt3a activation in a stoechiometric manner.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 50 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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- 抗原
- FZD5 (Frizzled Family Receptor 5 (FZD5))
- 别名
- Frizzled-5 (FZD5 产品)
- 别名
- C2orf31 Protein, HFZ5 Protein, 5330434N09Rik Protein, AI427138 Protein, Fz-5 Protein, Fz5 Protein, mFz5 Protein, Xfz5 Protein, frizzled5 Protein, frizzled5a Protein, fz5 Protein, fzd5-A Protein, fz2 Protein, fz8c Protein, fzd8c Protein, zg02 Protein, frizzled class receptor 5 Protein, frizzled class receptor 5 S homeolog Protein, FZD5 Protein, Fzd5 Protein, fzd5.S Protein, fzd5 Protein
- 背景
- Wnts are lipid-modified morphogens that control many processes during development, stem cell maintenance and homeostasis and their aberrant regulation has been linked to diseases in man including diabetes, neurodegeneration and cancer. Three distinct receptor families mediate Wnt signaling: Fzs, the single-pass LRP5/6 co-receptors and the atypical tyrosine kinase receptors Ror2 and Ryk. Frizzled proteins can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Wnt/Ca2+ pathways and planar cell polarity). The cysteine-rich domain (CRD) of the frizzled receptors situated on the extracellular part of the receptor is sufficient to bind the Wnt ligands.
- 分子量
- ~50kDa (SDS-PAGE)
- UniProt
- Q13467
- 途径
- WNT signaling
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