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PATZ1 Protein (His tag)

ZNF278 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735982
发货至: 中国
  • 抗原 See all PATZ1 (ZNF278) 蛋白
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This PATZ1 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ZNF278 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ZNF278 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    别名
    Znf278 (ZNF278 产品)
    别名
    ZNF278 Protein, MAZR Protein, PATZ Protein, RIAZ Protein, ZBTB19 Protein, ZSG Protein, dJ400N23 Protein, 8430401L15Rik Protein, AI447519 Protein, Mazr Protein, Patz Protein, Zfp278 Protein, Znf278 Protein, POZ/BTB and AT hook containing zinc finger 1 Protein, POZ/BTB and AT hook containing zinc finger 1 S homeolog Protein, POZ (BTB) and AT hook containing zinc finger 1 Protein, POZ-, AT hook-, and zinc finger-containing protein 1 Protein, PATZ1 Protein, patz1.S Protein, Patz1 Protein, LOC100153931 Protein
    背景
    The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(122)(p36.1q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
    分子量
    73.9 kDa
    NCBI登录号
    NP_055138
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