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GFI1 Protein (His tag)

GFI1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735931
发货至: 中国
  • 抗原 See all GFI1 蛋白
    GFI1 (Growth Factor Independent 1 (GFI1))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 1
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    大肠杆菌(E. Coli)
    标记
    This GFI1 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human ZNF163 (N-term HIS tag, transcript variant 2) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GFI1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    GFI1 (Growth Factor Independent 1 (GFI1))
    别名
    Znf163 (GFI1 产品)
    别名
    AW495828 Protein, Gfi-1 Protein, Pal-1 Protein, Pal1 Protein, GFI1 Protein, GFI-1 Protein, GFI1A Protein, SCN2 Protein, ZNF163 Protein, growth factor independent 1 Protein, growth factor independent 1 transcriptional repressor Protein, Gfi1 Protein, GFI1 Protein
    背景
    This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
    分子量
    45.1 kDa
    NCBI登录号
    NP_001120687
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