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USP2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

USP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2735099
发货至: 中国
  • 抗原 See all USP2 蛋白
    USP2 (Ubiquitin Specific Peptidase 2 (USP2))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 3
    • 2
    • 1
    • 1
    资源
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This USP2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human USP2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product USP2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    USP2 (Ubiquitin Specific Peptidase 2 (USP2))
    别名
    Usp2 (USP2 产品)
    别名
    UBP41 Protein, USP9 Protein, B930035K21Rik Protein, Ubp41 Protein, UBP-t Protein, UBP46 Protein, ubp52 Protein, ubp66 Protein, zgc:92134 Protein, ubiquitin specific peptidase 2 Protein, ubiquitin specific peptidase 2a Protein, USP2 Protein, Usp2 Protein, usp2a Protein
    背景
    This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
    分子量
    45.1 kDa
    NCBI登录号
    NP_741994
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