TIMP1 Protein (His tag)
-
- 抗原 See all TIMP1 蛋白
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This TIMP1 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
-
- Recombinant human TIMP1 protein expressed in HEK293.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 90 % , as determined by Coomassie stained SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg of protein as determine by the LAL method.
- Biological Activity Comment
- Human TIMP-1 inhibits the activity of activated mouse MMP-9 (100 ng/mL). The is IC50 = 34 ng/mL.
- Top Product
- Discover our top product TIMP1 蛋白
-
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) protein (Fc Tag)
TIMP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-205) protein (Fc Tag)TIMP1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TIMP Metallopeptidase Inhibitor 1 (TIMP1) protein (His tag)TIMP1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >80 % as determined by reducing SDS-PAGE.
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) protein (GST tag)TIMP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (Active) proteinTIMP1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (Active) proteinTIMP1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
TIMP Metallopeptidase Inhibitor 1 (TIMP1) proteinTIMP1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-205) protein (His tag)Crystallography grade TIMP1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- > 50 μg/mL
- 缓冲液
- 10 mM sodium Acetate, 150 mM NaCl, pH 5.0
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- 别名
- Timp1 (TIMP1 产品)
- 别名
- TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
- 背景
- This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
- 分子量
- 22 kDa
- NCBI登录号
- NP_003245
-
