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TIGAR Protein (TAT tag)

TIGAR 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
产品编号 ABIN2733723
发货至: 中国
  • 抗原 See all TIGAR 蛋白
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 5
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    大肠杆菌(E. Coli)
    标记
    This TIGAR protein is labelled with TAT tag.
    应用范围
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human TIGAR protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Pretreatment with TIGAR-TAT for 4 hrs, using a concentration range 0.1-5.0 ug/mL, protects U2OS cells from apoptosis induced by hydrogen peroxide.
    Top Product
    Discover our top product TIGAR 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    注意事项
    Resuspend the protein in the desired concentration in proper buffer
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
    别名
    Tigar (TIGAR 产品)
    别名
    AA793651 Protein, AI595337 Protein, C79710 Protein, C85509 Protein, Tigar Protein, Trp53 induced glycolysis repulatory phosphatase Protein, Tigar Protein
    背景
    This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.
    分子量
    31.6 kDa
    NCBI登录号
    NP_065108
    途径
    Warburg Effect
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