POT1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
(2 references)-
- 抗原 See all POT1 蛋白
- POT1 (Protection of Telomeres 1 (POT1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This POT1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human POT1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product POT1 蛋白
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Protection of Telomeres 1 (POT1) (AA 1-95) protein (GST tag)
POT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protection of Telomeres 1 (POT1) (AA 1-634) protein (Strep Tag)Crystallography grade POT1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Protection of Telomeres 1 (POT1) (AA 1-640) protein (Strep Tag)Crystallography grade POT1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity." in: PLoS ONE, Vol. 11, Issue 5, pp. e0156378, (2016) (PubMed).
: "The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs." in: Biochimie, Vol. 115, pp. 17-27, (2015) (PubMed).
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: "An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity." in: PLoS ONE, Vol. 11, Issue 5, pp. e0156378, (2016) (PubMed).
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- 抗原
- POT1 (Protection of Telomeres 1 (POT1))
- 别名
- Pot1 (POT1 产品)
- 别名
- HPOT1 Protein, POT1 Protein, DKFZp469P1825 Protein, pot1 Protein, 1500031H18Rik Protein, AI851169 Protein, Pot1 Protein, Pot1a Protein, protection of telomeres 1 Protein, protection of telomeres 1 L homeolog Protein, protection of telomeres 1A Protein, POT1 Protein, pot1.L Protein, Pot1a Protein, Pot1 Protein
- 背景
- This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
- 分子量
- 71.3 kDa
- NCBI登录号
- NP_056265
- 途径
- Cell Division Cycle, Telomere Maintenance
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