POLH Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all POLH 蛋白
- POLH (Polymerase (DNA Directed), eta (POLH))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This POLH protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human POLH / RAD30 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product POLH 蛋白
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Polymerase (DNA Directed), eta (POLH) (AA 1-414) protein (GST tag)
POLH 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Polymerase (DNA Directed), eta (POLH) (AA 1-713) protein (Strep Tag)Crystallography grade POLH 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Polymerase (DNA Directed), eta (POLH) (AA 1-694) protein (Strep Tag)Crystallography grade POLH 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- POLH (Polymerase (DNA Directed), eta (POLH))
- 别名
- Polh,rad30 (POLH 产品)
- 别名
- POLH Protein, fc50a12 Protein, wu:fc50a12 Protein, zgc:136881 Protein, zgc:152642 Protein, RAD30 Protein, RAD30A Protein, XP-V Protein, XPV Protein, polymerase (DNA directed), eta S homeolog Protein, DNA polymerase eta Protein, polymerase (DNA directed), eta Protein, putative DNA polymerase eta Protein, polymerase (DNA directed), eta (RAD 30 related) Protein, polh.S Protein, POLH Protein, polh Protein, Tb10.70.6190 Protein, LINJ_21_0690 Protein, Polh Protein, LOC100443019 Protein
- 背景
- This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 78.2 kDa
- NCBI登录号
- NP_006493
- 途径
- DNA Damage Repair
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