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PLOD2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

PLOD2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2729193
发货至: 中国
  • 抗原 See all PLOD2 蛋白
    PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 5
    • 1
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This PLOD2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human PLOD2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PLOD2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))
    别名
    Plod2 (PLOD2 产品)
    别名
    D530025C14Rik Protein, LH2 Protein, Plod-2 Protein, TLH Protein, procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 Protein, procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Protein, Plod2 Protein, PLOD2 Protein
    背景
    The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    分子量
    84.4 kDa
    NCBI登录号
    NP_891988
    途径
    SARS-CoV-2 Protein Interactome
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