PLA2G4A Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PLA2G4A 蛋白
- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PLA2G4A protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PLA2G4A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PLA2G4A 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
- 别名
- Pla2g4a (PLA2G4A 产品)
- 别名
- PLA2G4 Protein, cPLA2-alpha Protein, Pla2c Protein, Pla2g4 Protein, cPLA2 Protein, pla2g4 Protein, CPLA2 Protein, PLA2G4A Protein, PLA2 Protein, PLA2G1B Protein, cPLA2alpha Protein, pla2g4a Protein, si:dkey-97o5.1 Protein, phospholipase A2 group IVA Protein, phospholipase A2 group IVA L homeolog Protein, phospholipase A2, group IVA (cytosolic, calcium-dependent) Protein, phospholipase A2, group IVAb (cytosolic, calcium-dependent) Protein, PLA2G4A Protein, Pla2g4a Protein, pla2g4a.L Protein, pla2g4ab Protein
- 背景
- This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants.
- 分子量
- 85 kDa
- NCBI登录号
- NP_077734
- 途径
- Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
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