PIKFYVE Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
-
- 抗原 See all PIKFYVE 蛋白
- PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 4
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This PIKFYVE protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human PIP5K3 (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PIKFYVE 蛋白
-
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 1-451) protein (GST tag)
PIKFYVE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 342-451) protein (GST tag)PIKFYVE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) protein (His tag)PIKFYVE 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) proteinPIKFYVE 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PIKFYVE 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- 抗原
- PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))
- 别名
- Pip5k3 (PIKFYVE 产品)
- 别名
- pip5k3 Protein, wu:fo93c03 Protein, PIP5K3 Protein, fab1-like Protein, CFD Protein, FAB1 Protein, PIP5K Protein, ZFYVE29 Protein, 5230400C17Rik Protein, Pip5k Protein, Pip5k3 Protein, Pipk5k3 Protein, PipkIII Protein, p235 Protein, phosphoinositide kinase, FYVE finger containing Protein, phosphoinositide kinase, FYVE-type zinc finger containing Protein, phosphoinositide kinase, FYVE type zinc finger containing Protein, pikfyve Protein, PIKFYVE Protein, Pikfyve Protein
- 背景
- Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKfyve also has protein kinase activity. PIKfyve regulates endomembrane homeostasis and plays a role in the biogenesis of endosome carrier vesicles from early endosomes. Mutations in this gene cause corneal fleck dystrophy (CFD) an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma. Histologically, these flecks appear to be keratocytes distended with lipid and mucopolysaccharide filled intracytoplasmic vacuoles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].
- 分子量
- 62
- NCBI登录号
- NP_001171471
- 途径
- Inositol Metabolic Process
-
