PHKA2 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all PHKA2 蛋白
- PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PHKA2 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human PHKA2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PHKA2 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))
- 别名
- Phka2 (PHKA2 产品)
- 别名
- GSD9A Protein, PHK Protein, PYK Protein, PYKL Protein, XLG Protein, XLG2 Protein, PHKA2 Protein, 6330505C01Rik Protein, D330034O08 Protein, Phk Protein, phosphorylase kinase regulatory subunit alpha 2 Protein, phosphorylase kinase alpha 2 Protein, PHKA2 Protein, Phka2 Protein
- 背景
- Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010].
- 分子量
- 138.2 kDa
- NCBI登录号
- NP_000283
- 途径
- Cellular Glucan Metabolic Process
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