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PCDHGA12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

PCDHGA12 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2728393
发货至: 中国
  • 抗原 See all PCDHGA12 蛋白
    PCDHGA12 (Protocadherin gamma 12 (PCDHGA12))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    资源
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This PCDHGA12 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human PCDHGA12 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PCDHGA12 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PCDHGA12 (Protocadherin gamma 12 (PCDHGA12))
    别名
    Pcdhga12 (PCDHGA12 产品)
    别名
    CDH21 Protein, FIB3 Protein, PCDH-GAMMA-A12 Protein, Pcdh13 Protein, pc2c Protein, protocadherin gamma subfamily A, 12 Protein, PCDHGA12 Protein, Pcdhga12 Protein
    背景
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    分子量
    97.7 kDa
    NCBI登录号
    NP_003726
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