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OAS1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

OAS1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2727845
发货至: 中国
  • 抗原 See all OAS1 蛋白
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 5
    • 2
    • 1
    • 1
    资源
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This OAS1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human OAS1 / OIAS (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product OAS1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    别名
    Oas1,oias (OAS1 产品)
    别名
    OAS1 Protein, IFI-4 Protein, OIAS Protein, OIASI Protein, L3 Protein, Pp2a2 Protein, 2',5'-oligoadenylate synthetase 1 Protein, 2'-5'-oligoadenylate synthetase 1 Protein, 2'-5' oligoadenylate synthetase 1A Protein, protein phosphatase 2 catalytic subunit beta Protein, OAS1 Protein, Oas1a Protein, Ppp2cb Protein, Oas1 Protein
    背景
    This gene is induced by interferons and encodes a protein that synthesizes 2&apos,5&apos-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.
    分子量
    41.6 kDa
    NCBI登录号
    NP_002525
    途径
    Hepatitis C
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