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NSMCE2 Protein (His tag)

NSMCE2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2727651
发货至: 中国
  • 抗原 See all NSMCE2 蛋白
    NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
    蛋白类型
    Recombinant
    宿主
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    资源
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    大肠杆菌(E. Coli)
    标记
    This NSMCE2 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human NSMCE2 (full length, N-term HIS tag) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NSMCE2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
    别名
    Nsmce2 (NSMCE2 产品)
    别名
    1110014D18Rik Protein, AI661537 Protein, RGD1305156 Protein, C8orf36 Protein, MMS21 Protein, NSE2 Protein, ZMIZ7 Protein, Non-SMC element 2 Protein, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase Protein, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog Protein, Smc5-6 complex non-SMC subunit 2 Protein, Nsmce2 Protein, NSMCE2 Protein, nsmce2.L Protein, nse2 Protein
    背景
    This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.
    分子量
    27.8 kDa
    NCBI登录号
    NP_775956
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