NR1I3 Protein (His tag)
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- 抗原 See all NR1I3 蛋白
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NR1I3 protein is labelled with His tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NR1I3 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NR1I3 蛋白
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Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 2-59) protein (GST tag)
NR1I3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-352) protein (GST tag)NR1I3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-352) protein (Strep Tag)Crystallography grade NR1I3 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-358) protein (Strep Tag)Crystallography grade NR1I3 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) protein (His tag)NR1I3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 2-351), (partial) protein (His-SUMO Tag)NR1I3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the N-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- 别名
- Nr1i3 (NR1I3 产品)
- 别名
- AA209988 Protein, AI551208 Protein, CAR Protein, CAR-beta Protein, Care2 Protein, ESTM32 Protein, MB67 Protein, CAR1 Protein, CXR Protein, nuclear receptor subfamily 1 group I member 3 Protein, nuclear receptor subfamily 1, group I, member 3 Protein, NR1I3 Protein, Nr1i3 Protein
- 背景
- This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 40.3 kDa
- NCBI登录号
- NP_001070950
- 途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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