NLRP10 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all NLRP10 蛋白
- NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NLRP10 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human NLRP10 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Discover our top product NLRP10 蛋白
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NLR Family, Pyrin Domain Containing 10 (NLRP10) (AA 1-655) protein (Strep Tag)
Crystallography grade NLRP10 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
NLR Family, Pyrin Domain Containing 10 (NLRP10) (AA 1-673) protein (Strep Tag)Crystallography grade NLRP10 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Glial uptake of amyloid beta induces NLRP3 inflammasome formation via cathepsin-dependent degradation of NLRP10." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 205-15, (2014) (PubMed).
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: "Glial uptake of amyloid beta induces NLRP3 inflammasome formation via cathepsin-dependent degradation of NLRP10." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 205-15, (2014) (PubMed).
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- 抗原
- NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
- 别名
- Nlrp10 (NLRP10 产品)
- 别名
- CLR11.1 Protein, NALP10 Protein, NOD8 Protein, PAN5 Protein, PYNOD Protein, 6430548I20Rik Protein, Nalp10 Protein, Napl10 Protein, Pynod Protein, NLR family pyrin domain containing 10 Protein, NLR family, pyrin domain containing 10 Protein, NLRP10 Protein, Nlrp10 Protein
- 背景
- Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
- 分子量
- 74.9 kDa
- NCBI登录号
- NP_789791
- 途径
- Inflammasome
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