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MMP2 Protein (Transcript Variant 2) (His tag)

MMP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2726158
发货至: 中国
  • 抗原 See all MMP2 蛋白
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 20
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    资源
    • 23
    • 7
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This MMP2 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human MMP-2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product MMP2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    别名
    Mmp-2 (MMP2 产品)
    别名
    2-MMP Protein, CG1794 Protein, DM2-MMP Protein, Dm2-MMP Protein, Dmel\\CG1794 Protein, MMP2 Protein, anon-WO0118547.84 Protein, dm-2MMP Protein, dmmp2 Protein, l(2)02353 Protein, mmp2 Protein, wu:fa99h12 Protein, wu:fk89d01 Protein, fgmmp-2 Protein, Mmp-2 Protein, LOC100135793 Protein, Clg4a Protein, GelA Protein, MMP-2 Protein, CLG4 Protein, CLG4A Protein, MMP-II Protein, MONA Protein, TBE-1 Protein, matrix metallopeptidase 2 Protein, Matrix metalloproteinase 2 Protein, matrix metalloproteinase 2 Protein, matrix metalloproteinase-2 Protein, MMP2 Protein, Mmp2 Protein, mmp2 Protein, LOC657982 Protein, LOC100135793 Protein
    背景
    This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
    分子量
    72.0 kDa
    NCBI登录号
    NP_001121363
    途径
    Activation of Innate immune Response
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