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MIB1 Protein (Myc-DYKDDDDK Tag)

MIB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2725966
发货至: 中国
  • 抗原 See all MIB1 蛋白
    MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This MIB1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human MIB1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MIB1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Kwon, Dimitriadi, Terzic, Cable, Hart, Chitnis, Fischbeck, Burnett: "The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein." in: Molecular biology of the cell, Vol. 24, Issue 12, pp. 1863-71, (2013) (PubMed).

  • 抗原
    MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
    别名
    Mib1 (MIB1 产品)
    别名
    DIP-1 Protein, DIP1 Protein, LVNC7 Protein, MIB Protein, ZZANK2 Protein, ZZZ6 Protein, E430019M12Rik Protein, Mib Protein, mKIAA1323 Protein, dip-1 Protein, mib Protein, mindbomb Protein, cg5841 Protein, chunp6889 Protein, fe47f05 Protein, im:7148100 Protein, mib1 Protein, wu:fe47f05 Protein, CG5841 Protein, D-mib Protein, D-mib1 Protein, Dmel\CG5841 Protein, Dmib Protein, MIB1 Protein, Mib1 Protein, dmib1 Protein, l(3)72CDa Protein, l(3)72Db Protein, mib1/2 Protein, mind-bomb Protein, mindbomb E3 ubiquitin protein ligase 1 Protein, mindbomb E3 ubiquitin protein ligase 1 L homeolog Protein, mind bomb 1 Protein, MIB1 Protein, Mib1 Protein, mib1.L Protein, mib1 Protein
    背景
    This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
    分子量
    110 kDa
    NCBI登录号
    NP_065825
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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