KMO Protein (Myc-DYKDDDDK Tag)
(1 reference)-
- 抗原 See all KMO 蛋白
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This KMO protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
-
- Recombinant human Kynurenine 3-monooxygenase / KMO protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
-
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 39-219) protein (His-IF2DI Tag)
KMO 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-407) protein (GST tag)KMO 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486) protein (Strep Tag)Crystallography grade KMO 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-479) protein (Strep Tag)Crystallography grade KMO 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486), (full length) protein (His-SUMO Tag)KMO 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) protein (DYKDDDDK Tag)KMO 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO) (AA 1-486), (full length) protein (His tag)KMO 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
-
- 应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
-
The tag is located at the C-terminal.
- 限制
- 仅限研究用
-
- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
: "Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase." in: Assay and drug development technologies, Vol. 13, Issue 8, pp. 466-75, (2015) (PubMed).
-
: "Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase." in: Assay and drug development technologies, Vol. 13, Issue 8, pp. 466-75, (2015) (PubMed).
-
- 抗原
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
- 别名
- Kynurenine 3-Monooxygenase,kmo (KMO 产品)
- 别名
- AI046660 Protein, dJ317G22.1 Protein, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) Protein, kynurenine 3-monooxygenase Protein, Kmo Protein, KMO Protein
- 背景
- Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. [UniProtKB/Swiss-Prot Function]
- 分子量
- 55.6 kDa
- NCBI登录号
- NP_003670
-
