IRF9 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all IRF9 蛋白
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IRF9 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human IRF9 / ISGF3G protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IRF9 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- 别名
- Irf9,isgf3g (IRF9 产品)
- 别名
- IRF-9 Protein, ISGF3 Protein, ISGF3G Protein, p48 Protein, zgc:92097 Protein, Irf-9 Protein, Isgf3g Protein, interferon regulatory factor 9 Protein, IRF9 Protein, irf9 Protein, Irf9 Protein
- 背景
- Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [UniProtKB/Swiss-Prot Function]
- 分子量
- 43.5 kDa
- NCBI登录号
- NP_006075
- 途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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