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GSTa2 Protein (Myc-DYKDDDDK Tag)

GSTa2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722269
发货至: 中国
  • 抗原 See all GSTa2 蛋白
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 2
    • 1
    • 1
    资源
    • 4
    • 2
    • 2
    HEK-293 Cells
    标记
    This GSTa2 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human GSTA2 / GST2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GSTa2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    别名
    Gsta2,gst2 (GSTa2 产品)
    别名
    GSTA1 Protein, GST2 Protein, GSTA2-2 Protein, GTA2 Protein, GTH2 Protein, Gsta1 Protein, Gst2-2 Protein, Gstc-2 Protein, Gstc2 Protein, glutathione S-transferase alpha 2 Protein, glutathione S-transferase Protein, glutathione S-transferase, alpha 2 (Yc2) Protein, GSTA2 Protein, Gsta2 Protein
    背景
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
    分子量
    25.5 kDa
    NCBI登录号
    NP_000837
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