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GLE1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

GLE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2721895
发货至: 中国
  • 抗原 See all GLE1 蛋白
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 3
    • 1
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    HEK-293 Cells
    标记
    This GLE1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human GLE1 / GLE1L (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GLE1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    别名
    Gle1,gle1l (GLE1 产品)
    别名
    Dmel\\CG14749 Protein, GLE1 Protein, GLE1L Protein, LCCS Protein, LCCS1 Protein, hGLE1 Protein, Gle1l Protein, 4933405K21Rik Protein, AA553313 Protein, CG14749 gene product from transcript CG14749-RA Protein, nucleoporin GLE1 Protein, RNA export factor Gle1 Protein, GLE1, RNA export mediator Protein, GLE1 RNA export mediator Protein, GLE1 RNA export mediator (yeast) Protein, CG14749 Protein, CpipJ_CPIJ014147 Protein, SJAG_03847 Protein, GLE1 Protein, Gle1 Protein
    背景
    This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    79.7 kDa
    NCBI登录号
    NP_001003722
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