FMO3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- 抗原 See all FMO3 蛋白
- FMO3 (Flavin Containing Monooxygenase 3 (FMO3))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 1
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FMO3 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human FMO3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FMO3 蛋白
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Flavin Containing Monooxygenase 3 (FMO3) (AA 1-532) protein (GST tag)
FMO3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Flavin Containing Monooxygenase 3 (FMO3) (AA 2-532) protein (His tag)Crystallography grade FMO3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Flavin Containing Monooxygenase 3 (FMO3) (AA 2-534) protein (His tag)Crystallography grade FMO3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Flavin Containing Monooxygenase 3 (FMO3) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)FMO3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- FMO3 (Flavin Containing Monooxygenase 3 (FMO3))
- 别名
- Fmo3 (FMO3 产品)
- 别名
- MGC107820 Protein, FMOII Protein, TMAU Protein, dJ127D3.1 Protein, FM03 Protein, AW111792 Protein, flavin containing monooxygenase 3 Protein, flavin containing monooxygenase 3 L homeolog Protein, FMO3 Protein, fmo3 Protein, fmo3.L Protein, Fmo3 Protein
- 背景
- Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.[provided by RefSeq, Jan 2016].
- 分子量
- 59.9 kDa
- NCBI登录号
- NP_008825
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