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Filamin A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

FLNA 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2721188
发货至: 中国
  • 抗原 See all Filamin A (FLNA) 蛋白
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    资源
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This Filamin A protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Filamin-A (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FLNA 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Henkels, Mallets, Dennis, Gomez-Cambronero: "S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 4, pp. 1299-313, (2015) (PubMed).

  • 抗原
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    别名
    Filamin-A (FLNA 产品)
    别名
    ABP-280 Protein, ABPX Protein, CSBS Protein, CVD1 Protein, FLN Protein, FLN-A Protein, FLN1 Protein, FMD Protein, MNS Protein, NHBP Protein, OPD Protein, OPD1 Protein, OPD2 Protein, XLVD Protein, XMVD Protein, fb98b06 Protein, wu:fb98b06 Protein, wu:fd09g03 Protein, wu:fd49a06 Protein, Dilp2 Protein, F730004A14Rik Protein, Fln1 Protein, filamin-1 Protein, RGD1560614 Protein, MGC147094 Protein, CG3937 Protein, Cher Protein, Dmel\\CG3937 Protein, Fil Protein, joy Protein, sko Protein, filamin A Protein, filamin A, alpha (actin binding protein 280) Protein, filamin, alpha Protein, filamin-A Protein, cheerio Protein, FLNA Protein, flna Protein, Flna Protein, LOC587317 Protein, cher Protein, LOC100380643 Protein
    背景
    The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009].
    分子量
    280.6 kDa
    NCBI登录号
    NP_001104026
    途径
    TCR Signaling, Maintenance of Protein Location
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