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DNMT1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DNMT1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
产品编号 ABIN2719616
发货至: 中国
  • 抗原 See all DNMT1 蛋白
    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    Transcript Variant 1
    宿主
    • 5
    • 4
    • 2
    资源
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This DNMT1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human DNMT1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Biological Activity Comment
    DNMT1 activity verified in a biochemical assay:,DNMT1 activity verified in a biochemical assay:,DNMT1 activity verified in a biochemical assay:
    Top Product
    Discover our top product DNMT1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    > 50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
    别名
    Dnmt1 (DNMT1 产品)
    别名
    cb1075 Protein, cb983 Protein, dmnt1 Protein, fb05h01 Protein, mta Protein, wu:fb05h01 Protein, ADCADN Protein, AIM Protein, CXXC9 Protein, DNMT Protein, HSN1E Protein, MCMT Protein, DDM2 Protein, DECREASED DNA METHYLATION 2 Protein, DMT01 Protein, DMT1 Protein, DNA METHYLTRANSFERASE Protein, DNA METHYLTRANSFERASE 01 Protein, DNA METHYLTRANSFERASE 1 Protein, MET2 Protein, METHYLTRANSFERASE 2 Protein, METHYLTRANSFERASE I Protein, METI Protein, methyltransferase 1 Protein, Cxxc9 Protein, Dnmt Protein, Dnmt1o Protein, MTase Protein, Met-1 Protein, Met1 Protein, MommeD2 Protein, m.MmuI Protein, DNA methyltransferase 1 Protein, DNA (cytosine-5-)-methyltransferase 1 Protein, methyltransferase 1 Protein, DNA methyltransferase (cytosine-5) 1 Protein, DNMT1 Protein, dnmt1 Protein, Dnmt1 Protein, MET1 Protein
    背景
    This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
    分子量
    184.6 kDa
    NCBI登录号
    NP_001124295
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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