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FE65 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

APBB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2714775
发货至: 中国
  • 抗原 See all FE65 (APBB1) 蛋白
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 6
    • 1
    • 1
    资源
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This FE65 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human APBB1 / FE65 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product APBB1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    别名
    Apbb1,fe65 (APBB1 产品)
    别名
    FE65 Protein, MGC:9072 Protein, RIR Protein, apbb1 Protein, MGC80654 Protein, Fe65 Protein, Rir Protein, amyloid beta precursor protein binding family B member 1 Protein, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog Protein, amyloid beta (A4) precursor protein-binding, family B, member 1 Protein, APBB1 Protein, apbb1.L Protein, Apbb1 Protein
    背景
    The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer&aposs disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product&aposs nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer&aposs disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    分子量
    77.1 kDa
    NCBI登录号
    NP_001155
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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