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PLAUR Protein (Transcript Variant 2) (His tag)

PLAUR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2713803
发货至: 中国
  • 抗原 See all PLAUR 蛋白
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 2
    宿主
    • 26
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    资源
    • 22
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    HEK-293 Cells
    标记
    This PLAUR protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CD87 / uPAR (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product PLAUR 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    别名
    Cd87,upar (PLAUR 产品)
    别名
    Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein
    背景
    This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
    分子量
    32.6 kDa
    NCBI登录号
    NP_001005376
    途径
    Inositol Metabolic Process
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