抗原 See all CD81 蛋白

CD81

蛋白类型

Recombinant

宿主 12 2 1

人

资源 4 4 2 1 1 1 1 1

HEK-293 Cells

标记

This CD81 protein is labelled with Myc-DYKDDDDK Tag.

应用范围

Antibody Production (AbP), Standard (STD)

产品特性

Recombinant human CD81 / TAPA1 protein expressed in HEK293 cells.
Produced with end-sequenced ORF clone

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining

Top Product

Discover our top product CD81 蛋白

CD81 (CD81) (AA 25-127) protein (GST tag)

CD81 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

CD81 (CD81) (AA 110-150) protein (His-IF2DI Tag)

CD81 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

CD81 (CD81) (AA 1-236) protein (Strep Tag)

Crystallography grade CD81 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA

CD81 (CD81) (AA 1-236) protein (Strep Tag)

Crystallography grade CD81 宿主: 小鼠宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA

CD81 (CD81) protein (His tag)

CD81 宿主: 人宿主: Tobacco (Nicotiana benthamiana) Recombinant SDS

CD81 (CD81) protein (Fc Tag)

CD81 宿主: 人宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

CD81 (CD81) (AA 113-201) protein (His tag)

CD81 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 97 % SDS, WB, Imm, PC

CD81 (CD81) protein

CD81 宿主: 大鼠宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE

CD81 (CD81) protein

CD81 宿主: 人宿主: HEK-293 Cells Synthetic

CD81 (CD81) (AA 113-201) protein (hIgG-His-tag)

CD81 宿主: 人宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS

应用备注: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
说明: The tag is located at the C-terminal.
限制: 仅限研究用

浓度: 50 μg/mL
缓冲液: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
储存条件: -80 °C
储存方法: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Goetzl, Mustapic, Kapogiannis, Eitan, Lobach, Goetzl, Schwartz, Miller: "Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 11, pp. 3853-3859, (2016) (PubMed).

Winston, Goetzl, Akers, Carter, Rockenstein, Galasko, Masliah, Rissman: "Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile." in: Alzheimer's & dementia (Amsterdam, Netherlands), Vol. 3, pp. 63-72, (2016) (PubMed).

Kapogiannis, Boxer, Schwartz, Abner, Biragyn, Masharani, Frassetto, Petersen, Miller, Goetzl: "Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 589-96, (2015) (PubMed).

Richter, Dayaram, Gilmartin, Ganji, Pemmasani, Van Der Key, Shohet, Donehower, Kumar: "WIP1 phosphatase as a potential therapeutic target in neuroblastoma." in: PLoS ONE, Vol. 10, Issue 2, pp. e0115635, (2015) (PubMed).

Marquez-Jurado, Nogales, Zuñiga, Enjuanes, Almazán: "Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response." in: mBio, Vol. 6, Issue 2, pp. e00105, (2015) (PubMed).

Ning, Koh, Pan, Jeong: "Hepatocyte nuclear factor (HNF) 4α transactivation of cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in mice." in: Biochemical pharmacology, Vol. 94, Issue 1, pp. 46-52, (2015) (PubMed).

Srinivasan, Blackburn, Lahiri: "Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation." in: Drug design, development and therapy, Vol. 8, pp. 2409-21, (2015) (PubMed).

Fiandaca, Kapogiannis, Mapstone, Boxer, Eitan, Schwartz, Abner, Petersen, Federoff, Miller, Goetzl: "Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study." in: Alzheimer's & dementia : the journal of the Alzheimer's Association, (2014) (PubMed).

Myers, Maxwell, Wang: "Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS." in: Bioanalysis, Vol. 6, Issue 22, pp. 2969-83, (2014) (PubMed).

Lawrence, Conderino, Rieder: "Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: role of Jumonji C-domain containing protein 6 in RHA demethylation." in: Virology, Vol. 452-453, pp. 1-11, (2014) (PubMed).

Bando, Iguchi, Fukuoka, Yamamoto, Hidaka-Takeno, Okimura, Matsumoto, Suda, Nishizawa, Takahashi, Tojo, Takahashi: "Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. E1744-9, (2014) (PubMed).

Drosopoulos, Tang, Chao, Linardopoulos: "APC/C is an essential regulator of centrosome clustering." in: Nature communications, Vol. 5, pp. 3686, (2014) (PubMed).

Larsen, Munir, Woetmann, Frøsig, Odum, Svane, Becker, Andersen: "Functional characterization of Foxp3-specific spontaneous immune responses." in: Leukemia, Vol. 27, Issue 12, pp. 2332-40, (2013) (PubMed).

Zhao, Tian, Edeh, Brasier: "Quantitation of the dynamic profiles of the innate immune response using multiplex selected reaction monitoring-mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1513-29, (2013) (PubMed).

Radovanac, Morgner, Schulz, Blumbach, Patterson, Geiger, Mann, Krieg, Eckes, Fässler, Wickström: "Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response." in: The EMBO journal, Vol. 32, Issue 10, pp. 1409-24, (2013) (PubMed).

Kim, Lone, Saghatelian: "Analysis of the proteolysis of bioactive peptides using a peptidomics approach." in: Nature protocols, Vol. 8, Issue 9, pp. 1730-42, (2013) (PubMed).

Banerjee, de Freitas, Friggeri, Zmijewski, Liu, Abraham: "Intracellular HMGB1 negatively regulates efferocytosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 9, pp. 4686-94, (2011) (PubMed).

抗原: CD81
别名: Cd81,tapa1 (CD81 产品)
别名: Tapa-1 Protein, Tapa1 Protein, Tspan28 Protein, CVID6 Protein, S5.7 Protein, TAPA1 Protein, TSPAN28 Protein, CD81 molecule Protein, CD81 molecule b Protein, CD81 antigen Protein, Cd81 molecule Protein, CD81 Protein, cd81b Protein, Cd81 Protein
背景: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
分子量: 25.6 kDa
NCBI登录号: NP_004347
途径: Inositol Metabolic Process, Hepatitis C

CD81 Protein (CD81) (Myc-DYKDDDDK Tag)

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