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CKMT1B Protein (Myc-DYKDDDDK Tag)

CKMT1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712839
发货至: 中国
  • 抗原 See all CKMT1B 蛋白
    CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    HEK-293 Cells
    标记
    This CKMT1B protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CKMT protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CKMT1B 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
    别名
    Ckmt (CKMT1B 产品)
    别名
    CKMT Protein, CKMT1 Protein, UMTCK Protein, ckmt Protein, ckmt1 Protein, umtck Protein, CKMT1A Protein, creatine kinase, mitochondrial 1B Protein, creatine kinase, mitochondrial 1B S homeolog Protein, creatine kinase, mitochondrial 1B L homeolog Protein, CKMT1B Protein, ckmt1b.S Protein, ckmt1b.L Protein, ckmt1b Protein
    背景
    Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
    分子量
    43 kDa
    NCBI登录号
    NP_066270
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