CYP2D6 Protein (DYKDDDDK Tag)
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- 抗原 See all CYP2D6 蛋白
- CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CYP2D6 protein is labelled with DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CYP2D6 (C-term DDK tag, transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CYP2D6 蛋白
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Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 91-190) protein (GST tag)
CYP2D6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (AA 1-497) protein (Strep Tag)Crystallography grade CYP2D6 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CYP2D6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
- 别名
- Cyp2d6 (CYP2D6 产品)
- 别名
- CPD6 Protein, CYP2D Protein, CYP2D7AP Protein, CYP2D7BP Protein, CYP2D7P2 Protein, CYP2D8P2 Protein, CYP2DL1 Protein, CYPIID6 Protein, P450-DB1 Protein, P450C2D Protein, P450DB1 Protein, CYP2D42 Protein, MGC64445 Protein, cyp2d2 Protein, cyp2d6-a Protein, CYP2D6 Protein, cytochrome P450 family 2 subfamily D member 6 Protein, cytochrome P450, family 2, subfamily D, polypeptide 6 Protein, cytochrome 2D6 Protein, cytochrome P450 family 2 subfamily D member 6 S homeolog Protein, cytochrome P450 2D6 Protein, cytochrome P450 2D6-like Protein, CYP2D6 Protein, cyp2d6-b Protein, cyp2d6.S Protein, cyp2d6 Protein, LOC100988273 Protein
- 背景
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25 % of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme&aposs substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 57 kDa
- NCBI登录号
- NP_000097
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