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NCR3 Protein (Fc Tag)

NCR3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN2566796
发货至: 中国
  • 抗原 See all NCR3 蛋白
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 21
    • 2
    • 1
    • 1
    • 1
    资源
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This NCR3 protein is labelled with Fc Tag.
    应用范围
    Western Blotting (WB), ELISA
    产品特性

    Measured by its binding ability in a functional ELISA. Immobilized rh B7-H6 Fc Chimera at 1 μg/mL (100 μL/well), the concentration of rhNKp30 Fc Chimera that produces 50 % of the optimal binding response is found to be approximately 10 - 50 ng/mL.

    Fusion tag: C-Fc Tag

    纯度
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product NCR3 蛋白
  • 应用备注
    This recombinant protein can be used for WB, ELISA. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 mM tris, 100 mM glycine, pH 7.5
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    别名
    NCR3 (NCR3 产品)
    别名
    MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
    背景
    Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
    分子量
    39.5 kDa
    基因ID
    259197
    UniProt
    O14931
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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