RCAN2 Protein (AA 2-197, Isoform 2) (His tag)
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- 抗原 See all RCAN2 蛋白
- RCAN2 (Regulator of Calcineurin 2 (RCAN2))
- 蛋白类型
- Recombinant
- 产品特性
- Isoform 2, AA 2-197
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This RCAN2 protein is labelled with His tag.
- 应用范围
- ELISA, Western Blotting (WB), Mass Spectrometry (MS), Neutralization (Neut)
- 纯度
- ~95 %
- Top Product
- Discover our top product RCAN2 蛋白
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Regulator of Calcineurin 2 (RCAN2) (AA 1-197) protein (His tag)
RCAN2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Regulator of Calcineurin 2 (RCAN2) (AA 1-225) protein (GST tag)RCAN2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Regulator of Calcineurin 2 (RCAN2) (AA 1-197) protein (Strep Tag)Crystallography grade RCAN2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Regulator of Calcineurin 2 (RCAN2) (AA 1-197) protein (Strep Tag)Crystallography grade RCAN2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 mM sodium phosphate, 10 mM Tris, 500 mM NaCl, 25 mM imidazole, 2 mM MgCl2, 10 % gycerol
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- RCAN2 (Regulator of Calcineurin 2 (RCAN2))
- 别名
- RCAN2 (RCAN2 产品)
- 别名
- DSCR1L1 Protein, si:ch211-124g24.1 Protein, zgc:85746 Protein, RCAN2 Protein, DKFZp459H071 Protein, rcan2 Protein, CSP2 Protein, MCIP2 Protein, RCN2 Protein, ZAKI-4 Protein, ZAKI4 Protein, Csp2 Protein, Dscr1l1 Protein, Dcip2 Protein, Zaki-4 Protein, regulator of calcineurin 2 Protein, rcan2 Protein, RCAN2 Protein, Rcan2 Protein
- 背景
- Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle (1,2). Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin s activity (3). Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3 (3). RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome (4).
- 分子量
- 26 kDa (Calculated)
- 基因ID
- 53901
- OMIM
- 38328420
- UniProt
- Q9JHG2
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