GLP-1 蛋白
GLP-1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
< 98 % by SDS-PAGE gel and HPLC analyses.
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- 抗原 See all GLP-1 蛋白
- GLP-1 (Glucagon-like peptide 1 (GLP-1))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- HAEGTFTSDV SSYLEGQAAK EFIAWLVKGR G
- 纯度
- < 98 % by SDS-PAGE gel and HPLC analyses.
- 内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product GLP-1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing GLP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- GLP-1 (Glucagon-like peptide 1 (GLP-1))
- 别名
- GLP-1 (GLP-1 产品)
- 别名
- GLP1 Protein, GLP2 Protein, GRPP Protein, GLP-1 Protein, Glu Protein, PPG Protein, glucagon Protein, GCG Protein, Gcg Protein
- 背景
- GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic beta-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
- 基因ID
- 2641
- NCBI登录号
- NP_002045
- OMIM
- 4503945
- UniProt
- P01275
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