TNFRSF21 Protein (AA 371-655, Cytoplasmic Domain) (His tag)
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- 抗原 See all TNFRSF21 蛋白
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- 蛋白类型
- Recombinant
- 产品特性
- Cytoplasmic Domain, AA 371-655
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宿主
- 人, 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TNFRSF21 protein is labelled with His tag.
- 应用范围
- Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
- 纯度
- ~95 %
- Top Product
- Discover our top product TNFRSF21 蛋白
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Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)
TNFRSF21 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)TNFRSF21 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 89-170) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 47-214) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 47-349) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 373-655) protein (His-DYKDDDDK-Strep II Tag)TNFRSF21 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-349) protein (His tag)TNFRSF21 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-472) protein (GST tag)TNFRSF21 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-124) protein (GST tag)TNFRSF21 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-212) proteinTNFRSF21 宿主: 人 宿主: Human Recombinant SDS
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- 应用备注
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 1X PBS containing 10 % glycerol
- 注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -80 °C
- 储存方法
- Store in working aliquots at -70 °C.
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- 抗原
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- 别名
- DR6 (TNFRSF21 产品)
- 别名
- TNFRSF21 Protein, tnfrsf21 Protein, MGC146356 Protein, BM-018 Protein, CD358 Protein, DR6 Protein, AA959878 Protein, R74815 Protein, TR7 Protein, dr6 Protein, im:6795346 Protein, wu:fa55e01 Protein, wu:fb02e11 Protein, wu:fc29a09 Protein, wu:fi27h08 Protein, TNF receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily member 21 Protein, tumor necrosis factor receptor superfamily, member 21 Protein, TNFRSF21 Protein, tnfrsf21 Protein, Tnfrsf21 Protein
- 背景
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several death receptors including DR3, DR4, DR5, and DR6 have been identified. Like TNF-R1, DR6 (also known as TNFRSF21) interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed in human tissues and cell lines (2). Recently, DR6 was found to interact with an amino-terminal fragment of the Beta-amyloid protein (APP) in neurons, activating a caspase 6-dependent apoptotic event leading to axonal degeneration and pruning (3). The doublet observed in the SDS-PAGE is likely due to incomplete removal of the signal sequence.
- 分子量
- 36 kDa (Calculated)
- 基因ID
- 27242
- NCBI登录号
- NP_055267
- OMIM
- 7657039
- UniProt
- O75509
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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