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FcRn Protein (AA 24-297) (His tag,Strep Tag,Biotin)

FcRn 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
产品编号 ABIN2444126
发货至: 中国
  • 抗原 See all FcRn 蛋白
    FcRn (IgG receptor FcRn (FcRn))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 24-297
    宿主
    • 15
    • 6
    • 5
    • 3
    • 3
    • 1
    资源
    • 18
    • 4
    • 3
    • 3
    • 1
    • 1
    HEK-293 Cells
    标记
    This FcRn protein is labelled with His tag,Strep Tag,Biotin.
    品牌
    MABSol®,UltraLys
    序列
    AA 24-297
    特异性
    The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with biotins using standard chemical labeling method. A standard biotin reagent (13.5 angstroms) is used in this product.
    产品特性
    The subunit FCGRT carries a polyhistidine tag at the C-terminus. The subunit B2M carries a Strep II tag at the C-terminus. The protein has a calculated MW of 31.2 kDa (FCGRT), 13.1 kDa (B2M) . The protein migrates as 33 kDa (FCGRT), 13 kDa (B2M) respectively on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product FcRn 蛋白
  • 说明

    A chemically labeled biotinylated protein with ultra sensitivity.
    The product is produced using a chemical labeling approach. The primary amines in the side chains of lysine residues and the N-terminus of protein are conjugated with biotins.
    Chemical labeling usually results in multiple biotin attachment on a single protein molecule, which could potentially lead to higher detection sensitivity.

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
  • 抗原
    FcRn (IgG receptor FcRn (FcRn))
    别名
    FcRn (FcRn 产品)
    别名
    FCRN Protein, alpha-chain Protein, FcRn Protein, Fc fragment of IgG receptor and transporter Protein, Fc receptor, IgG, alpha chain transporter Protein, FCGRT Protein, Fcgrt Protein
    背景
    FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
    分子量
    31.2 kDa (FCGRT), 13.1 kDa (B2M)
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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