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S100A8 Protein (AA 1-93)

S100A8 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181719
发货至: 中国
  • 抗原 See all S100A8 蛋白
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    蛋白类型
    Recombinant
    产品特性
    AA 1-93
    宿主
    • 15
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    资源
    • 23
    • 3
    • 2
    • 2
    大肠杆菌(E. Coli)
    序列
    AA 1-93
    产品特性
    This protein carries no "tag". The protein has a calculated MW of 10.8 kDa. The protein migrates as 10.8 kDa under reducing (R) condition (SDS-PAGE).
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product S100A8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C- 8 °C) or 3 months (-20 °C to - 70 °C).
  • Gruda, Ruggeberg, OSullivan, Guliashvili, Scheirer, Golobish, Capponi, Chan: "Broad adsorption of sepsis-related PAMP and DAMP molecules, mycotoxins, and cytokines from whole blood using CytoSorb® sorbent porous polymer beads." in: PLoS ONE, Vol. 13, Issue 1, pp. e0191676, (2017) (PubMed).

  • 抗原
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    别名
    S100A8 (S100A8 产品)
    别名
    60B8AG Protein, CAGA Protein, CFAG Protein, CGLA Protein, CP-10 Protein, L1Ag Protein, MA387 Protein, MIF Protein, MRP8 Protein, NIF Protein, P8 Protein, Mrp8 Protein, S100A8 Protein, 60B8Ag Protein, AI323541 Protein, B8Ag Protein, CFAg Protein, Caga Protein, p8 Protein, MRP-8 Protein, S100 calcium binding protein A8 Protein, S100 calcium binding protein A8 (calgranulin A) Protein, S100A8 Protein, S100a8 Protein
    背景
    S100 calcium binding protein A8 (S100-A8) is also kown as Cystic fibrosis antigen, Migration inhibitory factor-related protein 8 60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MIF, MRP8, NIF and P8, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100A8 plays a role in various functions of myeloid cells by forming a heterocomplex with S100A9. S100A8 and S100A9 are known to be overexpressed in certain species of carcinomas. S100A8 may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. S100A8 plays an important role in differentiation of thyroid carcinoma possibly by forming a complex with S100A9. S100A8 and S100A9 may also play a key role in inflammation-associated cancer.
    分子量
    10.8 kDa
    途径
    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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