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NCR3 Protein (AA 19-135) (His tag)

NCR3 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181530
发货至: 中国
  • 抗原 See all NCR3 蛋白
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    蛋白类型
    Recombinant
    产品特性
    AA 19-135
    宿主
    • 21
    • 2
    • 1
    • 1
    • 1
    资源
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This NCR3 protein is labelled with His tag.
    序列
    AA 19-135
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 13.7 kDa. The protein migrates as 20-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product NCR3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    别名
    NKp30 (NCR3 产品)
    别名
    MGC133750 Protein, 1C7 Protein, CD337 Protein, LY117 Protein, MALS Protein, NKp30 Protein, Nkp30 Protein, natural cytotoxicity triggering receptor 3 Protein, NCR3 Protein, Ncr3 Protein
    背景
    Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
    分子量
    13.7 kDa
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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