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IL13 Receptor alpha 1 Protein (AA 26-340) (Fc Tag)

IL13RA1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
产品编号 ABIN2181338
发货至: 中国
  • 抗原 See all IL13 Receptor alpha 1 (IL13RA1) 蛋白
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    蛋白类型
    Recombinant
    产品特性
    AA 26-340
    宿主
    • 17
    • 10
    • 1
    • 1
    小鼠
    资源
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    HEK-293 Cells
    标记
    This IL13 Receptor alpha 1 protein is labelled with Fc Tag.
    序列
    AA 26-340
    产品特性
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 62.7 kDa. The protein migrates as 67-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >95 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL13RA1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原
    IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
    别名
    IL-13 R alpha 1 (IL13RA1 产品)
    别名
    CD213A2 Protein, CT19 Protein, IL-13R Protein, IL13BP Protein, CD213A1 Protein, IL-13Ra Protein, NR4 Protein, AI882074 Protein, CD213a1 Protein, IL-13r[a] Protein, Il13ra Protein, IL13RA1 Protein, il-13ra1 Protein, si:ch211-150g2.2 Protein, interleukin 13 receptor subunit alpha 2 Protein, interleukin 13 receptor subunit alpha 1 Protein, interleukin 13 receptor, alpha 1 Protein, interleukin 13 receptor, alpha 1-like Protein, IL13RA2 Protein, IL13RA1 Protein, Il13ra1 Protein, il13ra1 Protein, LOC100360218 Protein
    背景
    Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76 % aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
    分子量
    62.7 kDa
    NCBI登录号
    NP_598751
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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