Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4) (AA 1-327), (full length) (Active) 蛋白

ABIN2181286 产品详细信息, 供应商: Log in to see
  • immunoglobulin heavy constant gamma 4 (G4m marker)
  • IGHG4
AA 1-327, full length

HEK-293 Cells
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Supplier Product No.
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产品特性 This protein carries no "tag". The protein has a calculated MW of 40 kDa. The protein migrates as 40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
纯度 >85 % as determined by SDS-PAGE.
过滤 0.22 μm filtered
内毒素水平 Less than 1.0 EU per μg by the LAL method.
背景 Ig gamma-4 chain C region (IGHG4) is also known as IgG4 H Chain C Region, is a member of many immunoglobulin G developed and secreted by effective B cells. IgG4 is an antibody moleculer induced by infection. Immunoglobulins are composed of four peptides chain-two heavy gamma chains and two light chains. Ig gamma-4 chain C region / IGHG4 contains three constant regions of IgG4 H chain (CH1, CH2, CH3) and with a 12 aa hinge region between CH1 and CH2.
分子量 40 kDa
UniProt P01861
限制 仅限研究用
状态 Lyophilized
溶解方式 Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
缓冲液 50 mM Tris, 100 mM Glycine, pH 7.5
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
SDS-PAGE (SDS) image for Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4) (AA 1-327), (full length) (Active) protein (ABIN2181286) Human IgG4 H Chain C Region (Full Length), Tag Free on SDS-PAGE under reducing (R) co...
背景 Chen, Jiang, Sun, Han, Wang, Ye, Wang, Zou: "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." in: Journal of proteome research, Vol. 8, Issue 2, pp. 651-61, 2009 (PubMed).

Kristiansen, Bunkenborg, Gronborg, Molina, Thuluvath, Argani, Goggins, Maitra, Pandey: "A proteomic analysis of human bile." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 7, pp. 715-28, 2004 (PubMed).

Frangione, Milstein, Pink: "Structural studies of immunoglobulin G." in: Nature, Vol. 221, Issue 5176, pp. 145-8, 1970 (PubMed).

ODonnell, Frangione, Porter: "The disulphide bonds of the heavy chain of rabbit immunoglobulin G." in: The Biochemical journal, Vol. 116, Issue 2, pp. 261-8, 1970 (PubMed).